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LRP1 抗体 (pSer4523) (HRP)

This anti-LRP1 antibody is a 兔 多克隆 antibody detecting LRP1 in ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN801657
发货至: 中国

Quick Overview for LRP1 抗体 (pSer4523) (HRP) (ABIN801657)

抗原

See all LRP1 抗体
LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

适用

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人, 大鼠

宿主

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克隆类型

  • 85
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多克隆

标记

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This LRP1 antibody is conjugated to HRP

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer4523

    特异性

    This is the corresponding phosphorylation site in the following species: mouse ser(4524) rat ser(4524)

    交叉反应

    人, 大鼠

    预测反应

    Mouse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human LRP1 around the phosphorylation site of Ser4523

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

    别名

    LRP1

    背景

    Synonyms: APR, LRP, A2MR, CD91, APOER, LRP1A, TGFBR5, IGFBP3R, Prolow-density lipoprotein receptor-related protein 1, LRP-1, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, LRP1

    Background: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Functions as a receptor for Pseudomonas aeruginosa exotoxin A.

    基因ID

    4035

    UniProt

    Q07954

    途径

    Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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