LRP6 抗体 (pThr1479) (Cy5.5)
Quick Overview for LRP6 抗体 (pThr1479) (Cy5.5) (ABIN801638)
抗原
See all LRP6 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- pThr1479
- 
                                            交叉反应
- 人, 小鼠
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                                            预测反应
- Dog,Cow,Pig,Horse,Rabbit,Guinea Pig
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic phosphopeptide derived from human LRP6 around the phosphorylation site of Thr1479
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                                            亚型
- IgG
 
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                                            应用备注
- 
                        FCM 1:20-100
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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                                            别名
- LRP6
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                                            背景
- 
                        Synonyms: LRP6 Thr1479, LRP6 T1479, p-LRP6 Thr1479, p-LRP6 T1479, ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, Low density lipoprotein receptor related protein 6, LRP6_HUMAN, Low-density lipoprotein receptor-related protein 6, low-density lipoprotein receptor-related protein 6 precursor, LRP-6. Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]. 
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                                            基因ID
- 4040
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                                            UniProt
- O75581
- 
                                            途径
- WNT signaling, Tube Formation
 抗原
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