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LRP6 抗体 (pThr1479) (Cy5.5)

This anti-LRP6 antibody is a 兔 多克隆 antibody detecting LRP6 in WB, IF (p), IF (cc) 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN801638
发货至: 中国

Quick Overview for LRP6 抗体 (pThr1479) (Cy5.5) (ABIN801638)

抗原

See all LRP6 抗体
LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This LRP6 antibody is conjugated to Cy5.5

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
  • 抗原表位

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    pThr1479

    交叉反应

    人, 小鼠

    预测反应

    Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human LRP6 around the phosphorylation site of Thr1479

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

    别名

    LRP6

    背景

    Synonyms: LRP6 Thr1479, LRP6 T1479, p-LRP6 Thr1479, p-LRP6 T1479, ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, Low density lipoprotein receptor related protein 6, LRP6_HUMAN, Low-density lipoprotein receptor-related protein 6, low-density lipoprotein receptor-related protein 6 precursor, LRP-6.

    Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

    基因ID

    4040

    UniProt

    O75581

    途径

    WNT signaling, Tube Formation
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