IL12A 抗体
Our Local Distributor
北京 101111
Quick Overview for IL12A 抗体 (ABIN784573)
抗原
See all IL12A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Recognizes Interleukin-12 alpha / IL12A.
-
交叉反应 (详细)
-
Species reactivity (expected):Canine (Dog), Pig.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
-
免疫原
- Synthetic peptide - KLH conjugated of Human IL12A
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
-
-
- IL12A (Interleukin 12 alpha (IL12A))
-
别名
- Interleukin-12 alpha / IL12A
-
背景
- Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
-
基因ID
- 3592
-
NCBI登录号
- NP_000873
-
途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
-