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C3 抗体

This anti-C3 antibody is a 山羊 多克隆 antibody detecting C3 in IP, IHC (fro), EIA, IF 和 ID. Suitable for 小鼠.
产品编号 ABIN783937
发货至: 中国

Quick Overview for C3 抗体 (ABIN783937)

抗原

See all C3 抗体
C3 (Complement Component 3 (C3))

适用

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小鼠

宿主

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  • 1
山羊

克隆类型

  • 135
  • 49
多克隆

标记

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This C3 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunodiffusion (ID)
  • 纯化方法

    The IgG fraction is isolated and purified from the antiserum and contains the bulk of the defined antibody specificity. It is free of other serum proteins as tested by immunoelectrophoresis and double radial immunodiffusion

    免疫原

    C3c isolated and purified from pooled normal Mouse serum. Freund’s complete adjuvant is used in the first step of the immunization procedure.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore by adding 1.0 mL of sterile distilled water

    浓度

    10.0 mg/mL

    缓冲液

    PBS, pH 7.2 without preservatives and foreign proteins

    储存液

    Without preservative

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
  • 抗原

    C3 (Complement Component 3 (C3))

    别名

    Complement C3

    背景

    C3 is the most abundant complement protein in rat serum. Its biological function strongly resembles that of C3 in man and other laboratory animal species. It has a central role in the activation system being common to both pathways. Activation of C3 is achieved by very specific limited proteolysis resulting in the release of a number of degradation fragments. The anaphylotoxin C3a promotes smooth muscle contraction and increases vascular permeability: the large C3b fragment is involved in binding to the complement activator and can be interact with specific receptors to allow efficient clearance of the activating cell or particle, degradation fragments of C3b (C3bi, C3c, C3dg C3d) are important in receptor binding and clearance mechanisms, in virus neutralization and possibly in the immune response.Synonyms: CPAMD1, Complement component 3

    基因ID

    10116

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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