CCR2 抗体
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北京 101111
Quick Overview for CCR2 抗体 (ABIN783845)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody antibody detects ~42 kDa of CCR2.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide surrounding to amino acid 353 of rat CCR2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol and 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
- CD192 / CCR2
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背景
- Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.Synonyms: C-C CKR-2, C-C chemokine receptor type 2, CC-CKR-2, CCR-2, CMKBR2, MCP1-Receptor, Monocyte chemoattractant protein 1 receptor
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基因ID
- 729230
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NCBI登录号
- NP_001116513
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UniProt
- P41597
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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