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CCR2 抗体

The 兔 多克隆 anti-CCR2 antibody is suitable to detect CCR2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN783845
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCR2 抗体 (ABIN783845)

抗原

See all CCR2 抗体
CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

适用

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人, 小鼠, 大鼠

宿主

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  • 2
  • 1

克隆类型

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  • 2
多克隆

标记

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This CCR2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    This antibody antibody detects ~42 kDa of CCR2.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide surrounding to amino acid 353 of rat CCR2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol and 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
  • 抗原

    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

    别名

    CD192 / CCR2

    背景

    Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.Synonyms: C-C CKR-2, C-C chemokine receptor type 2, CC-CKR-2, CCR-2, CMKBR2, MCP1-Receptor, Monocyte chemoattractant protein 1 receptor

    基因ID

    729230

    NCBI登录号

    NP_001116513

    UniProt

    P41597

    途径

    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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