STAT1 抗体
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北京 101111
Quick Overview for STAT1 抗体 (ABIN783841)
抗原
See all STAT1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes both alpha (91 kDa) and beta (84 kDa) subunits of STAT1.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide surrounding amino acid 672 of rat Stat1
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亚型
- IgG
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anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 717-745), (C-Term) antibodySTAT1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB41406 unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 343-602) antibodySTAT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibodyKD Validated STAT1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4185 unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 114-143), (N-Term) antibodySTAT1 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibodySTAT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 513-712) antibodySTAT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 2-230) antibodySTAT1 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 2-230) antibodySTAT1 适用: 人, 猴 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 12C7 unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) antibodySTAT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
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- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
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别名
- STAT1
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背景
- STATs (signal transducers and activators of transcription) are a family of cytoplamic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signalling peptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6). Stat1, Stat3, Stat5a and Stat5b have wide activation profiles. Stat1 is activated by many different ligands including IFN family (IFN-a, IFN-b, IFN-r, and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF-1), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). Stat1 has two forms, the 91 kDa STAT1α and the 84 kDa STAT1β, which are coded by the same gene with splicing variant.Synonyms: Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84
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基因ID
- 6772
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NCBI登录号
- NP_009330
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UniProt
- P42224
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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