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NLRP6 抗体 (N-Term)

This anti-NLRP6 antibody is a 兔 多克隆 antibody detecting NLRP6 in WB 和 EIA. Suitable for 人.
产品编号 ABIN783709
发货至: 中国

Quick Overview for NLRP6 抗体 (N-Term) (ABIN783709)

抗原

See all NLRP6 抗体
NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

适用

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宿主

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克隆类型

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多克隆

标记

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This NLRP6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects NLRP6 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid peptide near the amino terminus of human NALP6
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

    别名

    NLRP6

    背景

    NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.Synonyms: LRR and PYD domains-containing protein 6, NACHT, NALP6, PYPAF5

    基因ID

    171389

    NCBI登录号

    NP_612202

    UniProt

    P59044

    途径

    Inflammasome
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