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- 抗原 See all NLRP6 抗体
- NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NLRP6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Recognizes human NLRP6.
- 交叉反应
- 人
- 纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
- 纯度
- >95 % (SDS-PAGE)
- 免疫原
- Recombinant human NLRP6 (NACHT domain).
- 克隆位点
- Clint-1
- 亚型
- IgG1
- Top Product
- Discover our top product NLRP6 Primary Antibody
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anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) (AA 351-450) antibody
NLRP6 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), ICC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) (AA 154-306) antibodyNLRP6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) antibodyNLRP6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) (AA 100-200) antibodyNLRP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) (AA 168-197), (N-Term) antibodyNLRP6 适用: 人 WB 宿主: 兔 Polyclonal RB33587 unconjugated
anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) (AA 168-197) antibodyNLRP6 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) (AA 343-372) antibodyNLRP6 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 6 (NLRP6) (N-Term) antibodyNLRP6 适用: 人 ELISA, WB, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
- 别名
- NLRP6/NALP6 (NLRP6 产品)
- 别名
- NLRP6 antibody, NALP6 antibody, AVR antibody, CLR11.4 antibody, NAVR antibody, NAVR/AVR antibody, PAN3 antibody, PYPAF5 antibody, AI504961 antibody, Avr antibody, Nalp6 antibody, Navr antibody, Navr/Avr antibody, Pypaf5 antibody, NLR family pyrin domain containing 6 antibody, NLR family, pyrin domain containing 6 antibody, NLRP6 antibody, Nlrp6 antibody
- 背景
- The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to caspase-1 activation. NLRP6/NALP6 is important for intestinal homeostasis by sensing pathogenic commensal bacteria and activating bactericidal activity of macrophages through secretion of IL-18. NLRP6 suppresses inflammation and carcinogenesis by regulating tissue repair and deletion of NLRP6 gene accelerated colitis-associated tumor growth in mice.
- UniProt
- P59044
- 途径
- Inflammasome
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