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EZH2 抗体 (N-Term)

This anti-EZH2 antibody is a 兔 多克隆 antibody detecting EZH2 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN783462
发货至: 中国

Quick Overview for EZH2 抗体 (N-Term) (ABIN783462)

抗原

See all EZH2 抗体
EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

适用

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人, 小鼠

宿主

  • 90
  • 32
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克隆类型

  • 76
  • 47
多克隆

标记

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This EZH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects EZH2 / KMT6 N-term. EZH2 antibody is predicted to not cross-react with EZH1.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    17 amino acid peptide near the amino terminus of human EZH2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

    别名

    EZH2 / KMT6

    背景

    EZH2 was initially identified as a homolog of the drosophila Enhancer of Zeste through exon trap screening of chromosome 21. Both EZH2 and the related protein EZH1 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair. Overexpression of EZH2 has been reported as a marker for advanced and metastatic cancers. Multiple isoforms of EZH2 are known to exist.Synonyms: ENX-1, Enhancer of zeste homolog 2, Histone-lysine N-methyltransferase EZH2, Lysine N-methyltransferase 6

    基因ID

    2146

    NCBI登录号

    NP_001190176

    UniProt

    Q15910

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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