COBRA1 抗体
Quick Overview for COBRA1 抗体 (ABIN782439)
抗原
See all COBRA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specific for the ~62k COBRA1 protein in Western blots of neonatal Rat brain lysate.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
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纯化方法
- Protein G Chromatography of Culture Supernatant.
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免疫原
- Recombinant full length Human COBRA1 purified from E. coli.
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亚型
- IgG1
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anti-Cofactor of BRCA1 (COBRA1) (Center) antibody
COBRA1 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 8-199) antibodyCOBRA1 适用: 人 WB, ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- COBRA1 (Cofactor of BRCA1 (COBRA1))
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别名
- NELF-B
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背景
- COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis (Zhong H et al., 2004).Synonyms: COBRA1, Cofactor of BRCA1, KIAA1182, NELFB, Negative elongation factor B
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基因ID
- 25920
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NCBI登录号
- NP_056271
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UniProt
- Q8WX92
抗原
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