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COBRA1 抗体 (AA 8-199) (FITC)

COBRA1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7161141
发货至: 中国
  • 抗原 See all COBRA1 抗体
    COBRA1 (Cofactor of BRCA1 (COBRA1))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-199
    适用
    • 46
    • 16
    • 8
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 7
    克隆类型
    • 41
    • 5
    多克隆
    标记
    • 24
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COBRA1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Negative elongation factor B protein (8-199AA)
    亚型
    IgG
    Top Product
    Discover our top product COBRA1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    COBRA1 (Cofactor of BRCA1 (COBRA1))
    别名
    NELFB (COBRA1 产品)
    别名
    LOC100219583 antibody, COBRA1 antibody, NELF-B antibody, bZ1O1.4 antibody, cobra1 antibody, cobra2 antibody, fe01e12 antibody, wu:fe01e12 antibody, zgc:55628 antibody, MGC131073 antibody, Cobra1 antibody, RGD1307832 antibody, A730008L03Rik antibody, AB041607 antibody, AI663983 antibody, Nelf-b antibody, cofactor of BRCA1 antibody, negative elongation factor complex member B antibody, negative elongation factor complex member B L homeolog antibody, LOC100219583 antibody, NELFB antibody, nelfb antibody, nelfb.L antibody, Nelfb antibody
    背景

    Background: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. Binds RNA which may help to stabilize the NELF complex on nucleic acid. In vitro, binds weakly to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1. May be able to induce chromatin unfolding.

    Aliases: NELFB antibody, COBRA1 antibody, KIAA1182 antibody, Negative elongation factor B antibody, NELF-B antibody, Cofactor of BRCA1 antibody

    UniProt
    Q8WX92
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