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SMAD3 抗体

SMAD3 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 7F3 unconjugated
产品编号 ABIN781908
发货至: 中国
  • 抗原 See all SMAD3 抗体
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    适用
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    人, 大鼠
    宿主
    • 235
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    小鼠
    克隆类型
    • 218
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    单克隆
    标记
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    This SMAD3 antibody is un-conjugated
    应用范围
    • 217
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to SMAD3.
    交叉反应 (详细)
    Species reactivity (expected):Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    SMAD3 antibody was raised against recombinant protein
    克隆位点
    7F3
    亚型
    IgG1
    Top Product
    Discover our top product SMAD3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0,43 mg/mL
    缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    别名
    SMAD3 (SMAD3 产品)
    别名
    HSPC193 antibody, HsT17436 antibody, JV15-2 antibody, LDS1C antibody, LDS3 antibody, MADH3 antibody, madh3 antibody, madh3a antibody, smad3 antibody, wu:fa99e03 antibody, XSmad3 antibody, XenMLP antibody, Xmad3 antibody, madh3-A antibody, Madh3 antibody, AU022421 antibody, Smad 3 antibody, mad3 antibody, madh3b antibody, zgc:92234 antibody, SMAD family member 3 antibody, SMAD family member 3a antibody, SMAD family member 3 L homeolog antibody, SMAD family member 3b antibody, SMAD3 antibody, smad3a antibody, smad3.L antibody, Smad3 antibody, smad3b antibody
    背景
    SMAD3, a transcriptional regulator, is activated by TGF-beta and Activin 1 receptor kinase. SMAD3 recognizes an 8 bp palindromic sequence GTCTAGAC. Upon phosphorylation at two extreme C-terminal serines, SMAD3 is translocated into the nucleus where is forms complexes other SMAD proteins, depending on the activation pathway, and regulates the transcription of target genes.Synonyms: JV15-2, MAD homolog 3, MAD-3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, SMAD family member 3, SMAD-3
    基因ID
    4088
    NCBI登录号
    NP_001138574
    UniProt
    P84022
    途径
    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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