Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
1.0 mg/mL
缓冲液
PBS, pH 7.4, containing 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
抗原
PKLR
(Pyruvate Kinase, Liver and RBC (PKLR))
别名
PKLR
背景
PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. The PKLR gene encodes the L- and R-type isoenzymes through alternative splicing events under the control of different promoters. The L-type isoform also exists as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young.Synonyms: PK1, PKL, Pyruvate kinase 1, Pyruvate kinase R/L, Pyruvate kinase isozymes R/L, R-type/L-type pyruvate kinase, Red cell/liver pyruvate kinase