PKC alpha 抗体
Quick Overview for PKC alpha 抗体 (ABIN781344)
抗原
See all PKC alpha (PKCa) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Cytoplasm
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纯化方法
- Protein G-Sepharose affinity purified.
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免疫原
- Recombinant fragment of human PRKCA (C-terminus).
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亚型
- IgG
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应用备注
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50µg/50µl
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缓冲液
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
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别名
- PRKCA
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背景
- PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
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分子量
- 50kDa
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NCBI登录号
- NM_002737
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途径
- WNT signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
抗原
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