HNF4A 抗体
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北京 101111
Quick Overview for HNF4A 抗体 (ABIN781302)
抗原
See all HNF4A 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Nucleus
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纯化方法
- Protein G-Sepharose affinity purified
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免疫原
- Recombinant fragment of Human HNF4A (C-terminus).
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亚型
- IgG
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应用备注
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50µg/50µl
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缓冲液
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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别名
- HNF4A
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背景
- HNF4 (Hepatocyte Nuclear Factor 4) is a nuclear receptor protein belonging to the steroid hormone receptor superfamily. HNF4 is commonly expressed in the liver and plays a critical role in liver development by establishing and maintaining hepatocyte differentiation. In human, two isoforms of HNF4 exists, alpha and gamma. HNF4 alpha is transcriptionally controlled transcription factor, which binds to DNA sites required for the transcription of alpha 1- antitrypsin, Apo CIII, transthyretin genes, and HNF1 alpha.
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分子量
- 53kDa
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途径
- AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
抗原
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