FIP200 抗体
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北京 101111
Quick Overview for FIP200 抗体 (ABIN781248)
抗原
See all FIP200 (RB1CC1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Nucleus
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纯化方法
- Protein G-Sepharose affinity purified
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免疫原
- Recombinant fragment of Human RB1CC1 (N-terminus).
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亚型
- IgG
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应用备注
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50µg/50µl
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缓冲液
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
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别名
- RB1CC1
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背景
- The RB1CC1 protein is a key regulator of the tumor suppressor gene RB1.It is localized in the nucleus and has been proposed to be a transcriptionfactor because of its nuclear localization signal, leucine zipper motif, andcoiled-coil structure. 20% of primary breast cancers contain mutations inRB1CC1 which shows characteristics of a classic tumor suppressor gene.
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分子量
- 40kDa
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NCBI登录号
- NM_014781
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途径
- Regulation of Cell Size, Autophagy
抗原
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