VAV2 抗体 (AA 401-500) (FITC)
Our Local Distributor
北京 101111
Quick Overview for VAV2 抗体 (AA 401-500) (FITC) (ABIN763308)
抗原
See all VAV2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 401-500
-
预测反应
- Human,Mouse,Rat,Dog,Cow,Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human VAV2
-
亚型
- IgG
-
-
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 552-868) antibody
VAV2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F5D3 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyKD Validated VAV2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3270 unconjugated Recombinant Antibody
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56694 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (Internal Region) antibodyVerified VAV2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 108-157), (pTyr142) antibodyVAV2 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 宿主: 绵羊 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 570-700) antibodyVAV2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 612-691) antibodyVAV2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))
-
别名
- VAV2
-
背景
-
Synonyms: Oncogene VAV2, Protein vav 2, VAV 2, Vav 2 oncogene, VAV2 oncogene, VAV2_HUMAN.
Background: VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.
-
基因ID
- 7410
-
途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
-
