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Nicastrin 抗体 (AA 21-120)

There is 1 publication for this product available. The 兔 多克隆 anti-Nicastrin antibody is suitable to detect Nicastrin in samples from 小鼠. It has been validated for WB, ELISA, ICC, IF (cc), IF (p), IHC (p) 和 IHC (fro).
产品编号 ABIN761801
发货至: 中国
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Quick Overview for Nicastrin 抗体 (AA 21-120) (ABIN761801)

抗原

See all Nicastrin (NCSTN) 抗体
Nicastrin (NCSTN)

适用

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小鼠

宿主

  • 65
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克隆类型

  • 46
  • 21
多克隆

标记

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This Nicastrin antibody is un-conjugated

应用范围

  • 52
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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    AA 21-120

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Nicastrin

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Ku, Li, Gao, Zhang, Yan, Ji, Li, Sang: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." in: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).

  • 抗原

    Nicastrin (NCSTN)

    别名

    Nicastrin

    背景

    Synonyms: ATAG1874, Nicastrin, NCSTN, KIAA0253, UNQ1874/PRO4317

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

    基因ID

    23385

    UniProt

    Q92542

    途径

    Notch Signaling, Neurotrophin Signaling Pathway
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