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Nicastrin 抗体 (C-Term)

Name: Nicastrin 抗体 (C-Term)
SKU: ABIN6263547
Availability: OutOfStock

NCSTN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of brain using NCSTN antibody. (Nicastrin 抗体 (C-Term))

ABIN6276511 at 1/100 staining Human urothelial cancer tissue by IHC-P. (Nicastrin 抗体 (C-Term))

IHC

2 images

产品编号 ABIN6263547

发货至: 中国

Datasheet as PDF

抗原 See all Nicastrin (NCSTN) 抗体

Nicastrin (NCSTN)
抗原表位
15

2

2

2

2

2

1

1

1

1

1

1

1

1

1
C-Term
适用
37

32

21

6

6

5

1

1
人, 小鼠, 大鼠
宿主
51

2
兔
Compatible Secondaries
克隆类型
43

10
多克隆
标记
20

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1
This Nicastrin antibody is un-conjugated
应用范围
39

13

13

8

7

3

3

3

2

2

2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

NCSTN Antibody detects endogenous levels of total NCSTN.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human NCSTN, corresponding to a region within C-terminal amino acids.

亚型

IgG

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anti-Nicastrin (NCSTN) (AA 429-669) antibody
NCSTN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 21-120) antibody
NCSTN 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 99-133) antibody
NCSTN 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB53031 unconjugated

anti-Nicastrin (NCSTN) (AA 1-689) antibody
NCSTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated

anti-Nicastrin (NCSTN) (AA 420-655) antibody
NCSTN 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 35-534) antibody
NCSTN 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nicastrin (NCSTN) (C-Term) antibody
NCSTN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Nicastrin (NCSTN) (Center) antibody
NCSTN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

Nicastrin (NCSTN)

别名

NCSTN (NCSTN 产品)

别名

CG7012 antibody, Dmel\\CG7012 antibody, Nct antibody, Nic antibody, S5A antibody, ST96B antibody, agro antibody, dNct antibody, nic antibody, NCSTN antibody, DKFZp469O2418 antibody, APH2 antibody, 9430068N19Rik antibody, AA727311 antibody, Aph2 antibody, D1Dau13e antibody, Kiaa0253 antibody, mKIAA0253 antibody, nicastrin antibody, Nicastrin antibody, NCSTN antibody, nct antibody, ncstn antibody, CpipJ_CPIJ001617 antibody, Ncstn antibody, aph-2 antibody

背景

Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
Gene: NCSTN

分子量

77kDa

基因ID

23385

UniProt

Q92542

途径

Notch Signaling, Neurotrophin Signaling Pathway