WWTR1 抗体
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北京 101111
Quick Overview for WWTR1 抗体 (ABIN8125763)
抗原
See all WWTR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- WWTR1 Antibody
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特异性
- WWTR1 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
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别名
- WWTR1
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背景
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Background: domain:Binds to transcription factors via its WW domain.,domain:The PDZ-binding motif is essential for stimulated gene transcription. It localizes the protein into both punctate nuclear foci and plasma membrane-associated complexes.,function:Functions as a transcriptional coactivator.,PTM:Phosphorylated. Phosphorylation results in the inhibition of transcriptional coactivation through YWHAZ-mediated nuclear export.,similarity:Contains 1 WW domain.,subcellular location:Concentrates along specific portions of the plasma membrane, and accumulates in punctate nuclear bodies. When phosphorylated, is retained in cytoplasm by YWHAZ.,subunit:Binds to SLC9A3R2 via the PDZ motif at the plasma membrane. Binds to YWHAZ in vivo and in vitro through the phosphoserine-binding motif RSHSSP.,tissue specificity:Highly expressed in kidney, heart, placenta and lung.,
Gene Name: WWTR1 TAZ
Protein Name: WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
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基因ID
- 25937
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UniProt
- Q9GZV5
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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