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RECQL2 抗体 (AA 1080-1160)

This 兔 多克隆 antibody specifically detects RECQL2 in WB 和 ELISA. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN8125745
发货至: 中国
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Quick Overview for RECQL2 抗体 (AA 1080-1160) (ABIN8125745)

抗原

See all RECQL2 (WRN) 抗体
RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

适用

人, 大鼠, 小鼠

宿主

  • 44
  • 17
兔

克隆类型

  • 42
  • 19
多克隆

标记

  • 30
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RECQL2 antibody is un-conjugated

应用范围

  • 35
  • 21
  • 19
  • 15
  • 9
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 12
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1080-1160

    原理

    WRN Antibody

    特异性

    This antibody detects endogenous levels of Human WRN

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human WRN AA range: 1080-1160

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

    别名

    WRN

    背景

    Synonyms: Werner syndrome ATP-dependent helicase (EC 3.6.4.12; DNA helicase, RecQ-like type 3; RecQ3; Exonuclease WRN; EC 3.1.-.-; RecQ protein-like 2)

    Background: Werner syndrome RecQ like helicase(WRN) Homo sapiens This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [provided by RefSeq, Jul 2008],

    Gene Name: WRN RECQ3 RECQL2

    Protein Name: WRN

    基因ID

    7486

    UniProt

    Q14191

    途径

    DNA Damage Repair
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