Tyrosinase-Related Protein 1 抗体 (Cleaved-Leu80)
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Quick Overview for Tyrosinase-Related Protein 1 抗体 (Cleaved-Leu80) (ABIN8125498)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Leu80
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原理
- CATB (Cleaved-Leu80) Antibody
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特异性
- This antibody detects endogenous levels of Human CATB (Cleaved-Leu80, protein was cleaved amino acid sequence between 79-80)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human CATB (Cleaved-Leu80)
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亚型
- IgG
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Tyrosinase-Related Protein 1 (TYRP1)
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别名
- CATB
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背景
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Synonyms: Cathepsin B (EC 3.4.22.1, APP secretase, APPS, Cathepsin B1) [Cleaved into: Cathepsin B light chain, Cathepsin B heavy chain]
Background: catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.,function:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.,similarity:Belongs to the peptidase C1 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.,
Gene Name: CTSB CPSB
Protein Name: CATB (Cleaved-Leu80)
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基因ID
- 1508
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UniProt
- P07858
抗原
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