TBCB 抗体
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北京 101111
Quick Overview for TBCB 抗体 (ABIN8125428)
抗原
See all TBCB 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TBCB Antibody
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特异性
- TBCB Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein
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亚型
- IgG
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anti-Tubulin Folding Cofactor B (TBCB) antibody
TBCB 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) (AA 1-244) antibodyTBCB 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) antibodyTBCB 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) antibodyTBCB 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) (AA 31-130) antibodyTBCB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) (AA 1-244) antibodyTBCB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) (AA 42-70), (N-Term) antibodyTBCB 适用: 人 WB 宿主: 兔 Polyclonal RB39901 unconjugated
anti-Tubulin Folding Cofactor B (TBCB) (AA 37-86) antibodyTBCB 适用: 人, 小鼠, Cow, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) (C-Term) antibodyTBCB 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor B (TBCB) (N-Term) antibodyTBCB 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TBCB (Tubulin Folding Cofactor B (TBCB))
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别名
- TBCB
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背景
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Background: function:Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.,PTM:Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome.,similarity:Belongs to the TBCB family.,similarity:Contains 1 CAP-Gly domain.,subcellular location:Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.,subunit:Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex, interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state. Cofactors B and E can form a heterodimer which binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers. Binds to GAN.,tissue specificity:Found in most tissues.,
Gene Name: TBCB CG22 CKAP1
Protein Name: Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B)
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基因ID
- 1155
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UniProt
- Q99426
抗原
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