TFE3 抗体 (AA 100-200)
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Quick Overview for TFE3 抗体 (AA 100-200) (ABIN8125277)
抗原
See all TFE3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-200
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原理
- TFE3 mouse mAb
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特异性
- This antibody detects endogenous levels of TFE3 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 100 - 200 of the human TFE3 protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | IP, 0. 5 μg-1:4 μg antibody for 200 μg-1:400 μg extracts of whole cells.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- TFE3 (Transcription Factor E3 (TFE3))
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别名
- TFE3
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背景
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Synonyms: Transcription factor E3, Class E basic helix-loop-helix protein 33 (bHLHe33) , BHLHE33, TFE3
Background: transcription factor binding to IGHM enhancer 3 (TFE3) Homo sapiens This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma) , NONO (non-POU domain containing, octamer-binding) , and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1) , among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
Gene Name: TFE3
Protein Name: TFE3
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基因ID
- 7030
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UniProt
- P19532
抗原
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