TCF7 抗体
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Quick Overview for TCF7 抗体 (ABIN8125271)
抗原
See all TCF7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TCF7 Rabbit mAb
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特异性
- This antibody detects endogenous levels of TCF7 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) antibody
TCF7 适用: 人 WB, IHC, IP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 200-250) antibodyTCF7 适用: 人, 小鼠 WB, IHC, ICC 宿主: 兔 Monoclonal BLR228K unconjugated Recombinant Antibody
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 287-384) antibodyTCF7 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 287-384) antibodyTCF7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 228-277) antibodyTCF7 适用: 人, Cow, 豚鼠, 马, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) antibodyTCF7 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (Middle Region) antibodyTCF7 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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别名
- TCF7
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背景
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Synonyms: TCF7, TCF1, Transcription factor 7, TCF-7, T-cell-specific transcription factor 1, T-cell factor 1, TCF-1
Background: alternative products:2 series of isoforms, L and S, are produced by use of alternative promoter usage. Additional isoforms seem to exist, function:Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4 (+) CD8 (+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1. , induction:By TCF7L2 and CTNNB1. , sequence caution:Wrong choice of frame. , similarity:Belongs to the TCF/LEF family. , similarity:Contains 1 HMG box DNA-binding domain. , subunit:Binds the armadillo repeat of CTNNB1 and forms a stable complex. Interacts with AES, TLE1, TLE2, TLE3 and TLE4. , tissue specificity:Predominantly in T-cells. Also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. ,
Gene Name: TCF7
Protein Name: TCF7
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基因ID
- 6932
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UniProt
- P36402
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途径
- WNT signaling
抗原
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