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TCF7 抗体

TCF7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7075952
发货至: 中国
  • 抗原 See all TCF7 抗体
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    适用
    • 55
    • 39
    • 17
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 51
    • 4
    • 2
    克隆类型
    • 51
    • 6
    多克隆
    标记
    • 36
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This TCF7 antibody is un-conjugated
    应用范围
    • 41
    • 18
    • 14
    • 5
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse TCF7
  • 应用备注
    IHC/IF (M,R) 1:600-1:1200/1:600-1:1200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    别名
    TCF7 (TCF7 产品)
    别名
    TCF-1 antibody, AI465550 antibody, Tcf1 antibody, Xtcf-1 antibody, Xtcf1 antibody, tcf-1 antibody, tcf1 antibody, tcf7 antibody, transcription factor 7 antibody, transcription factor 7, T cell specific antibody, transcription factor 7 S homeolog antibody, TCF7 antibody, Tcf7 antibody, tcf7 antibody, tcf7.S antibody
    背景
    TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
    基因ID
    21414
    NCBI登录号
    NP_001300910
    UniProt
    Q00417
    途径
    WNT signaling
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