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Topoisomerase II alpha 抗体 (AA 1400-1531)

This 小鼠 单克隆 antibody specifically detects Topoisomerase II alpha in IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8125247
发货至: 中国
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Quick Overview for Topoisomerase II alpha 抗体 (AA 1400-1531) (ABIN8125247)

抗原

See all Topoisomerase II alpha (TOP2A) 抗体
Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

适用

  • 247
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  • 1
人, 小鼠, 大鼠

宿主

  • 195
  • 53
小鼠

克隆类型

  • 146
  • 102
单克隆

标记

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This Topoisomerase II alpha antibody is un-conjugated

应用范围

  • 176
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  • 68
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  • 44
  • 27
  • 23
  • 20
  • 14
  • 13
  • 3
  • 2
  • 1
Immunohistochemistry (IHC)

克隆位点

AB1403
  • 抗原表位

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    • 9
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    • 2
    • 2
    • 2
    • 2
    • 1
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    AA 1400-1531

    原理

    Topoisomerase IIα mouse mAb

    特异性

    The antibody can specifically recognize human Topoisomerase IIα protein.

    纯化方法

    The antibody was purified by affinity chromatography using a specific immunogen.

    免疫原

    A synthetic peptide corresponding to the amino acid region 1400 - 1531 of the human Topoisomerase IIalpha protein.

    亚型

    IgG
  • 应用备注

    IHC, 1:200-1:400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

    别名

    Topoisomerase IIalpha

    背景

    Synonyms: alpha isozyme, ATP hydrolyzing DNA topoisomerase II alfa, DNA gyrase, DNA topoisomerase (ATP hydrolyzing) , DNA topoisomerase 2 alpha, DNA topoisomerase 2-alpha, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA topoisomerase II, DNA Topoisomerase2, TOP 2A, TOP2, TOP2A, TOP2A_HUMAN, Topoisomerase DNA II alpha 170 kDa, TP2A

    Background: Topoisomerase IIα (Topo IIα) is a nuclear protein with a molecular weight of 170 kDa. It belongs to the topoisomerase family and is expressed in proliferating cells. The main function is to maintain the spatial conformation of DNA and ensure its function. It is mainly used for the study of drug resistance.

    Gene Name: TOP2A

    Protein Name: Topoisomerase IIα

    基因ID

    7153

    UniProt

    P11388

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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