TLR3 抗体 (pTyr759)
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北京 101111
Quick Overview for TLR3 抗体 (pTyr759) (ABIN8125237)
抗原
See all TLR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr759
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原理
- TLR3 (Phospho Tyr759) Antibody
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特异性
- This antibody detects endogenous levels of TLR3 (Phospho-Tyr759) at Human, Mouse,Rat
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human TLR3 (Phospho-Tyr759)
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TLR3 (Toll-Like Receptor 3 (TLR3))
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别名
- TLR3
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背景
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Synonyms: Toll-like receptor 3 (CD antigen CD283)
Background: The protein encoded byThis gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate
Gene Name: TLR3
Protein Name: TLR3 (Phospho-Tyr759)
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基因ID
- 7098
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UniProt
- O15455
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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