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- 抗原 See all TLR3 抗体
- TLR3 (Toll-Like Receptor 3 (TLR3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TLR3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)
- 纯化方法
- Anti-TLR3 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR3 from dog, human and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR3 from other sources has not been determined.
- 免疫原
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Immunogen: TLR3 Antibody was produced in mice prepared by repeated immunizations with a peptide corresponding to internal amino acid sequences in the human protein TLR3.
Immunogen Type: Peptide
- 克隆位点
- 40C1285-6
- 亚型
- IgG1
- Top Product
- Discover our top product TLR3 Primary Antibody
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anti-Toll-Like Receptor 3 (TLR3) (AA 404-532) antibody
TLR3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 464-647) antibodyTLR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 801-905) antibodyTLR3 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 24-217) antibodyTLR3 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6F3G4 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 135-297) antibodyTLR3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) antibodyTLR3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 55-70) antibodyTLR3 适用: 人, 猴, 山羊, 绵羊 WB, IHC, FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal 40C1285-6 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 750-800), (pTyr759) antibodyTLR3 适用: 人 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry Dilution: 10 μg/mL
Application Note: Anti-TLR3 Antibody is suitable for use in Flow (CS), Flow (I), IF/ICC, IHC (p), IP and WB. Expect a band approximately 120 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: 2 μg/10^6 cells
Flow Cytometry Dilution: 2-4 μg/10^6 cells
Western Blot Dilution: 1-3 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- TLR3 (Toll-Like Receptor 3 (TLR3))
- 别名
- TLR3 (TLR3 产品)
- 别名
- CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
- 背景
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Synonyms: Toll-like receptor 3, CD283
Background: Anti-TLR3 Antibody detects human TLR3. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1-10) have been described. TLR3 cDNA codes for a protein with approximate molecular weight of 120 kDa. TLR3 has a restricted expression pattern being expressed in dendritic cells (DC). TLR3 mRNA expression was detected by in situ hybridization in DC and lymph nodes . The expression of TLR3 in a single cell type may indicate a specific role for this molecule in a restricted setting. Anti-TLR3 Antibody is ideal for investigators involved in cytokines and growth factor research.
Gene Name: TLR3
- 基因ID
- 7098
- NCBI登录号
- NP_003256
- UniProt
- O15455
- 途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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