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FGFRL1 抗体 (AA 231-330) (Biotin)

This anti-FGFRL1 antibody is a 兔 多克隆 antibody detecting FGFRL1 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN761683
发货至: 中国

Quick Overview for FGFRL1 抗体 (AA 231-330) (Biotin) (ABIN761683)

抗原

See all FGFRL1 抗体
FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FGFRL1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 231-330

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FGFR5/FGFRL1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

    别名

    FGFR5

    背景

    Synonyms: FGF homologous factor receptor, FGF receptor like protein 1, FGFR 5, FGFR like protein, FGFR5, FGFRL1, FHFR, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor like 1, FGRL1_HUMAN.

    Background: FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between FGFRL1 and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found.

    基因ID

    53834

    途径

    RTK signaling
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