STAT2 抗体
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北京 101111
Quick Overview for STAT2 抗体 (ABIN8124688)
抗原
See all STAT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Stat2 Rabbit mAb
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特异性
- This antibody detects endogenous levels of Stat2 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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别名
- Stat2
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背景
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Synonyms: STAT2, Signal transducer and activator of transcription 2, p113
Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN) , this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G) , in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Gene Name: STAT2
Protein Name: Stat2
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基因ID
- 6773
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UniProt
- P52630
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途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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