RPA1 抗体
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北京 101111
Quick Overview for RPA1 抗体 (ABIN8124316)
抗原
See all RPA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RFA1 Antibody
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特异性
- This antibody detects endogenous levels of Human,Monkey,Mouse,Rat RFA1
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human RFA1
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RPA1 (Replication Protein A1, 70kDa (RPA1))
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别名
- RFA1
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背景
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Synonyms: Replication protein A 70 kDa DNA-binding subunit (RP-A p70, Replication factor A protein 1, RF-A protein 1, Single-stranded DNA-binding protein)
Background: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,
Gene Name: RPA1 REPA1 RPA70
Protein Name: RFA1
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基因ID
- 6117
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UniProt
- P27694
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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