PDK3 抗体 (AA 170-250)
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Quick Overview for PDK3 抗体 (AA 170-250) (ABIN8124177)
抗原
See all PDK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-250
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原理
- PDK3 Antibody
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特异性
- PDK3 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 170-250
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亚型
- IgG
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibody
PDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB23090 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 1-30), (N-Term) antibodyPDK3 适用: 人 WB 宿主: 兔 Polyclonal RB3039 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibodyPDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 137-406) antibodyPDK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (Center) antibodyPDK3 适用: 人 ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 74-123) antibodyPDK3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔, Pig, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (C-Term) antibodyPDK3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, Pig, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 人 WB 宿主: 小鼠 Monoclonal 431CT6-1 unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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别名
- PDK3
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背景
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Background: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH.The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Gene Name: PDK3 PDHK3
Protein Name: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3)
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基因ID
- 5165
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UniProt
- Q15120
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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