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PDK3 抗体 (AA 174-263)

Cited in 3+ publications. The 小鼠 单克隆 anti-PDK3 antibody (Clone 2B11) (ABIN562161) specifically detects PDK3 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN562161
发货至: 中国
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Quick Overview for PDK3 抗体 (AA 174-263) (ABIN562161)

抗原

See all PDK3 抗体
PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

适用

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宿主

  • 60
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小鼠

克隆类型

  • 60
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单克隆

标记

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This PDK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

2B11
  • 抗原表位

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    AA 174-263

    原理

    Mouse monoclonal antibody raised against a partial recombinant PDK3.

    序列

    GDTNPVHPKH IGSIDPTCNV ADVVKDAYET AKMLCEQYYL VAPELEVEEF NAKAPDKPIQ VVYVPSHLFH MLFELFKNSM RATVELYEDR

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    PDK3 (AAH15948, 174 a.a. ~ 263 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hwang, Wu, Harris: "Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet." in: The FEBS journal, Vol. 279, Issue 10, pp. 1883-93, (2012) (PubMed).

    Jeoung, Harris: "Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice." in: American journal of physiology. Endocrinology and metabolism, Vol. 295, Issue 1, pp. E46-54, (2008) (PubMed).

    Lu, Lin, Chen, Lai, Tsai: "Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance." in: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28106-14, (2008) (PubMed).

  • 抗原

    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

    别名

    PDK3

    背景

    Full Gene Name: pyruvate dehydrogenase kinase, isozyme 3
    Synonyms:

    基因ID

    5165

    途径

    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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