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PDK3 抗体 (N-Term)

PDK3 适用: 人 WB 宿主: 兔 Polyclonal RB3039 unconjugated
产品编号 ABIN391038
发货至: 中国
  • 抗原 See all PDK3 抗体
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    抗原表位
    • 9
    • 9
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 32
    • 31
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 50
    • 3
    克隆类型
    • 50
    • 3
    多克隆
    标记
    • 30
    • 6
    • 5
    • 4
    • 4
    • 4
    This PDK3 antibody is un-conjugated
    应用范围
    • 46
    • 36
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PDK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDK3.
    克隆位点
    RB3039
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDK3 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Halim, Mcfate, Mohyeldin, Okagaki, Korotchkina, Patel, Jeoung, Harris, Schell, Verma: "Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons." in: Glia, Vol. 58, Issue 10, pp. 1168-76, (2010) (PubMed).

    McFate, Mohyeldin, Lu, Thakar, Henriques, Halim, Wu, Schell, Tsang, Teahan, Zhou, Califano, Jeoung, Harris, Verma: "Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 33, pp. 22700-8, (2008) (PubMed).

  • 抗原
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    别名
    PDK3 (PDK3 产品)
    别名
    pdk3 antibody, PDK3 antibody, 2610001M10Rik antibody, AI035637 antibody, zgc:158702 antibody, pyruvate dehydrogenase kinase 3 antibody, pyruvate dehydrogenase kinase, isozyme 3a antibody, pyruvate dehydrogenase kinase, isoenzyme 3 antibody, fragile site, 5-azacytidine type, common, fra(1)(q12) antibody, pyruvate dehydrogenase kinase, isozyme 3b antibody, PDK3 antibody, Pdk3 antibody, pdk3a antibody, pdk3 antibody, FRA1J antibody, pdk3b antibody
    背景
    PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    分子量
    46939
    基因ID
    5165
    NCBI登录号
    NP_001135858, NP_005382
    UniProt
    Q15120
    途径
    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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