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PKC 抗体 (AA 450-550)

The 小鼠 单克隆 anti-PKC antibody (Clone AB2366) (ABIN8124064) specifically detects PKC in WB, IF 和 ELISA. The antibody is reactive with 人, 小鼠, 大鼠, Cow 和 兔 samples.
产品编号 ABIN8124064
发货至: 中国
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Quick Overview for PKC 抗体 (AA 450-550) (ABIN8124064)

抗原

See all PKC 抗体
PKC (Protein Kinase C (PKC))

适用

  • 22
  • 18
  • 18
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 兔

宿主

  • 19
  • 4
小鼠

克隆类型

  • 14
  • 9
单克隆

标记

  • 23
This PKC antibody is un-conjugated

应用范围

  • 23
  • 14
  • 13
  • 11
  • 8
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA

克隆位点

AB2366
  • 抗原表位

    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 450-550

    原理

    PKC mouse mAb

    特异性

    This antibody detects endogenous levels of PKC protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 450 - 550 of the human PKC protein.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    PKC (Protein Kinase C (PKC))

    别名

    PKC

    背景

    Synonyms: Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, Protein kinase C beta type, PKC-B, PKC-beta, PRKCB, PKCB, PRKCB1, Protein kinase C gamma type, PKC-gamma, PRKCG, PKCG

    Background: protein kinase C alpha (PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes. [provided by RefSeq, Jul 2

    Gene Name: PRKCA PRKCB PRKCG

    Protein Name: PKC

    基因ID

    5578

    UniProt

    P17252

    途径

    TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Phototransduction
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