PKC 抗体 (AA 450-550)
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北京 101111
Quick Overview for PKC 抗体 (AA 450-550) (ABIN8124064)
抗原
See all PKC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 450-550
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原理
- PKC mouse mAb
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特异性
- This antibody detects endogenous levels of PKC protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 450 - 550 of the human PKC protein.
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亚型
- IgG
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应用备注
- WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- PKC (Protein Kinase C (PKC))
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别名
- PKC
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背景
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Synonyms: Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, Protein kinase C beta type, PKC-B, PKC-beta, PRKCB, PKCB, PRKCB1, Protein kinase C gamma type, PKC-gamma, PRKCG, PKCG
Background: protein kinase C alpha (PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes. [provided by RefSeq, Jul 2
Gene Name: PRKCA PRKCB PRKCG
Protein Name: PKC
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基因ID
- 5578
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UniProt
- P17252
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途径
- TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Phototransduction
抗原
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