PKC 抗体 (AA 623-672)
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Quick Overview for PKC 抗体 (AA 623-672) (ABIN1532523)
抗原
See all PKC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 623-672
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原理
- PKC Antibody
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特异性
- PKC Polyclonal Antibody detects endogenous levels of PKC protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PKC. AA range:623-672
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亚型
- IgG
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anti-Protein Kinase C (PKC) (pSer660) antibody
PKC 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5450 unconjugated Recombinant Antibody
anti-Protein Kinase C (PKC) (AA 623-672) antibodyPKC 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C (PKC) (pan), (pThr497) antibodyPKC 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C (PKC) (pThr497) antibodyPKC 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PKC (Protein Kinase C (PKC))
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别名
- PKC
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背景
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Synonyms: PRKCA, PKCA, PRKACA, Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCB, PKCB, PRKCB1, Protein kinase C beta type, PKC-B, PKC-beta, PRKCD, Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, PRKCE, PKCE, Protein kinase
Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2
Gene Name: PRKCA/PRKCB/PRKCD/PRKCE/PRKCG/PRKCH/PRKCQ/PRKCZ
Protein Name: Protein kinase C alpha type/Protein kinase C beta type/Protein kinase C delta type/Protein kinase C epsilon type/Protein kinase C gamma type/Protein kinase C eta type/Protein kinase C theta type/Protein kinase C zeta type
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分子量
- 76 kDa
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基因ID
- 5578, 5579, 5580
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OMIM
- 176960
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UniProt
- P17252
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途径
- TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Phototransduction
抗原
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