PKC 抗体 (C-Term)
This 小鼠 单克隆 antibody specifically detects PKC in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7860719
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for PKC 抗体 (C-Term) (ABIN7860719)
抗原
See all PKC 抗体
PKC
(Protein Kinase C (PKC))
适用
人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
标记
This PKC antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
克隆位点
133
-
-
抗原表位
- C-Term
-
原理
- Protein Kinase C α / PRKCA Antibody
-
特异性
- Protein Kinase C alpha (PKC°™) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the °™ isoform of PKC°™ and binds to a sequence at the C terminus of PKC°™ to detect its expression in vitro.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Full-length protein corresponding to PKC alpha. Recognizes sequence PQFVHPILQSAV at the C terminus at PKCα.
-
亚型
- IgG2a, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- PKC (Protein Kinase C (PKC))
-
别名
- Protein Kinase C α
-
背景
-
PKC alpha, PKC-A, PKC-alpha, PKCA, PRKCA, Protein kinase C alpha, Protein kinase C alpha type
Normal human kidney or tonsil tissue. HEK293 whole cell lysates.
-
分子量
- 77kDa
-
基因ID
- 5578, 531704, 708867
-
UniProt
- P17252
-
途径
- TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Interaction of EGFR with phospholipase C-gamma, Phototransduction
抗原
-
You are here:
