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POU2AF1 抗体 (AA 201-250)

The 兔 多克隆 anti-POU2AF1 antibody is suitable to detect POU2AF1 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, ELISA 和 IF.
产品编号 ABIN8123907
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for POU2AF1 抗体 (AA 201-250) (ABIN8123907)

抗原

See all POU2AF1 抗体
POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

适用

人, 小鼠, 大鼠

宿主

  • 102
  • 56
  • 2
兔

克隆类型

  • 84
  • 76
多克隆

标记

  • 71
  • 9
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This POU2AF1 antibody is un-conjugated

应用范围

  • 112
  • 85
  • 50
  • 30
  • 26
  • 26
  • 24
  • 20
  • 19
  • 12
  • 11
  • 7
  • 1
  • 1
Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 46
    • 18
    • 15
    • 15
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    AA 201-250

    原理

    Bob 1 Antibody

    特异性

    The antibody detects endogenous Bob 1

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic peptide from human protein at AA range: 201-250

    亚型

    IgG
  • 应用备注

    IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

    别名

    Bob 1

    背景

    Synonyms: POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1, BOB-1, OCA-B, OCT-binding factor 1)

    Background: disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3,11)(q27,q23) with BCL6.,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.,PTM:Ubiquitinated, mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the POU2AF1 family.,tissue specificity:B-cell specific.,

    Gene Name: POU2AF1 OBF1

    Protein Name: POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1)

    基因ID

    5450

    UniProt

    Q16633
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