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POLH 抗体

This 兔 多克隆 antibody specifically detects POLH in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8123858
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for POLH 抗体 (ABIN8123858)

抗原

See all POLH 抗体
POLH (Polymerase (DNA Directed), eta (POLH))

适用

  • 55
  • 22
  • 13
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 55
  • 3
兔

克隆类型

  • 57
  • 1
多克隆

标记

  • 21
  • 5
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  • 3
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This POLH antibody is un-conjugated

应用范围

  • 37
  • 13
  • 13
  • 11
  • 10
  • 9
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    POLH Antibody

    特异性

    POLH Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    POLH (Polymerase (DNA Directed), eta (POLH))

    别名

    POLH

    背景

    Background: This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],

    Gene Name: POLH RAD30 RAD30A XPV

    Protein Name: DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)

    基因ID

    5429

    UniProt

    Q9Y253

    途径

    DNA Damage Repair
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