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POLB 抗体 (acLys72)

This 兔 多克隆 antibody specifically detects POLB in WB 和 ELISA. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN8123855
发货至: 中国
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Quick Overview for POLB 抗体 (acLys72) (ABIN8123855)

抗原

See all POLB 抗体
POLB (Polymerase (DNA Directed), beta (POLB))

适用

  • 83
  • 49
  • 49
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  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 1
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人, 大鼠, 小鼠

宿主

  • 80
  • 3
兔

克隆类型

  • 61
  • 21
多克隆

标记

  • 32
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This POLB antibody is un-conjugated

应用范围

  • 60
  • 31
  • 16
  • 16
  • 14
  • 13
  • 12
  • 12
  • 6
  • 3
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 12
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    acLys72

    原理

    DNA pol β (Acetyl Lys72) Antibody

    特异性

    This antibody detects endogenous levels of Human,Mouse,Rat DNA pol β (Acetyl Lys72)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized peptide derived from human DNA pol beta (Acetyl Lys72)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    POLB (Polymerase (DNA Directed), beta (POLB))

    别名

    DNA pol beta

    背景

    Synonyms: DNA polymerase beta (EC 2.7.7.7, EC 4.2.99.-)

    Background: catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,

    Gene Name: POLB

    Protein Name: DNA pol β (Acetyl Lys72)

    基因ID

    5423

    UniProt

    P06746

    途径

    DNA Damage Repair
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