Nibrin 抗体 (pSer343)
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Quick Overview for Nibrin 抗体 (pSer343) (ABIN8123328)
抗原
See all Nibrin (NBN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer343
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原理
- p95/NBS1 (Phospho Ser343) Antibody
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特异性
- This antibody detects endogenous levels of Human Mouse p95 or NBS1 (phospho-Ser343)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human p95 (Ser343)
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亚型
- IgG
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Nibrin (NBN)
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别名
- p95/NBS1
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背景
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Synonyms: Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1)
Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008],
Gene Name: NBN NBS NBS1 P95
Protein Name: p95/NBS1 (Ser343)
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基因ID
- 4683
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UniProt
- O60934
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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