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Nibrin 抗体 (pSer343)

The 兔 多克隆 anti-Nibrin antibody is suitable to detect Nibrin in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN8123328
发货至: 中国
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Quick Overview for Nibrin 抗体 (pSer343) (ABIN8123328)

抗原

See all Nibrin (NBN) 抗体
Nibrin (NBN)

适用

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人, 小鼠

宿主

  • 142
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兔

克隆类型

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  • 70
多克隆

标记

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This Nibrin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 49
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    pSer343

    原理

    p95/NBS1 (Phospho Ser343) Antibody

    特异性

    This antibody detects endogenous levels of Human Mouse p95 or NBS1 (phospho-Ser343)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized phosho peptide around human p95 (Ser343)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Nibrin (NBN)

    别名

    p95/NBS1

    背景

    Synonyms: Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1)

    Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008],

    Gene Name: NBN NBS NBS1 P95

    Protein Name: p95/NBS1 (Ser343)

    基因ID

    4683

    UniProt

    O60934

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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