Nibrin 抗体 (AA 435-754)
(2 references)-
- 抗原 See all Nibrin (NBN) 抗体
- Nibrin (NBN)
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抗原表位
- AA 435-754
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nibrin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- KLPSINKSKD RASQQQQTNS IRNYFQPSTK KRERDEENQE MSSCKSARIE TSCSLLEQTQ PATPSLWKNK EQHLSENEPV DTNSDNNLFT DTDLKSIVKN SASKSHAAEK LRSNKKREMD DVAIEDEVLE QLFKDTKPEL EIDVKVQKQE EDVNVRKRPR MDIETNDTFS DEAVPESSKI SQENEIGKKR ELKEDSLWSA KEISNNDKLQ DDSEMLPKKL LLTEFRSLVI KNSTSRNPSG INDDYGQLKN FKKFKKVTYP GAGKLPHIIG GSDLIAHHAR KNTELEEWLR QEMEVQNQHA KEESLADDLF RYNPYLKRRR
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBS1/NBS1/NBN (NP_002476.2).
- 亚型
- IgG
- Top Product
- Discover our top product NBN Primary Antibody
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anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7E4C2 unconjugated
anti-Nibrin (NBN) (AA 467-615) antibodyNBN 适用: 人, 大鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7E4A2 unconjugated
anti-Nibrin (NBN) (AA 461-754) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-Nibrin (NBN) (AA 461-754) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Nibrin (NBN) (AA 183-460) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E7 unconjugated
anti-Nibrin (NBN) (AA 183-460) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Nibrin (NBN) (AA 183-460) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated
anti-Nibrin (NBN) (AA 645-754) antibodyNBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-Nibrin (NBN) antibodyKO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nibrin (NBN) (AA 714-745), (C-Term) antibodyNBN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:1000,IHC,1:50 - 1:100
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
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: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
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- 抗原
- Nibrin (NBN)
- 别名
- NBN (NBN 产品)
- 别名
- NBN antibody, AT-V1 antibody, AT-V2 antibody, ATV antibody, NBS antibody, NBS1 antibody, P95 antibody, Nbs1 antibody, im:6911679 antibody, zgc:194152 antibody, nibrin antibody, NBN antibody, nbn antibody, Nbn antibody
- 背景
- Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.,NBN,AT-V1,AT-V2,ATV,NBS,NBS1,P95,nibrin,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,NBN
- 分子量
- 84 kDa
- 基因ID
- 4683
- UniProt
- O60934
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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