NBR1 抗体
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北京 101111
Quick Overview for NBR1 抗体 (ABIN8123261)
抗原
See all NBR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NBR1 Antibody
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特异性
- The antibody detects endogenous NBR1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Recombinant Protein of NBR1
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亚型
- IgG
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应用备注
- IHC 1:50-300. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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别名
- NBR1
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背景
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Synonyms: Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2, Neighbor of BRCA1 gene 1 protein, Protein 1A1-3B)
Background: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],
Gene Name: NBR1 1A13B KIAA0049 M17S2 MIG19
Protein Name: Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
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基因ID
- 4077
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UniProt
- Q14596
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途径
- Autophagy
抗原
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