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NBR1 抗体

NBR1 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 4C6 unconjugated
产品编号 ABIN7250371
发货至: 中国
  • 抗原 See all NBR1 抗体
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    适用
    • 18
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 13
    • 7
    小鼠
    克隆类型
    • 16
    • 4
    单克隆
    标记
    • 20
    This NBR1 antibody is un-conjugated
    应用范围
    • 17
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Monoclonal Antibody
    纯化方法
    Protein A purification
    免疫原
    Recombinant Protein of NBR1
    克隆位点
    4C6
    亚型
    IgG
    Top Product
    Discover our top product NBR1 Primary Antibody
  • 应用备注
    IHC 1:50-300, IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    别名
    NBR1 (NBR1 产品)
    别名
    fa99f08 antibody, wu:fa99f08 antibody, MGC69008 antibody, NBR1 antibody, 1A1-3B antibody, M17S2 antibody, mKIAA0049 antibody, Ca125 antibody, RGD1311421 antibody, neighbor of brca1 gene 1a antibody, neighbor of BRCA1 gene 1 L homeolog antibody, NBR1, autophagy cargo receptor antibody, neighbor of Brca1 gene 1 antibody, nbr1a antibody, nbr1.L antibody, NBR1 antibody, Nbr1 antibody
    背景
    The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.
    UniProt
    Q14596
    途径
    Autophagy
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