MUC5AC 抗体
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Quick Overview for MUC5AC 抗体 (ABIN8123071)
抗原
See all MUC5AC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mucin 5AC Rabbit mAb
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特异性
- This antibody detects endogenous levels of Mucin 5AC protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) (AA 5528-5627) antibody
MUC5AC 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 8H8G6 unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) (AA 28-327) antibodyMUC5AC 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 6C9D11 unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) antibodyMUC5AC 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) antibodyMUC5AC 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal 45M1 unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) (AA 5528-5627) antibodyMUC5AC 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7E9D8 unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) (AA 601-700) antibodyMUC5AC 适用: 人 IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) (AA 4848-5030) antibodyMUC5AC 适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) (C-Term) antibodyMUC5AC 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) antibodyMUC5AC 适用: 人 IHC 宿主: 小鼠 Monoclonal 109M unconjugated Recombinant Antibody
anti-Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC) (AA 430-549) antibodyMUC5AC 适用: 小鼠 IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
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别名
- Mucin 5AC
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背景
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Synonyms: Mucin-5AC, Gastric mucin, Major airway glycoprotein, Mucin-5 subtype AC, tracheobronchial, Tracheobronchial mucin, MUC5, MUC5AC
Background: domain:The cysteine residues in the Cys-rich subdomain repeats are not involved in disulfide bonding. , function:Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particules that are subsequently removed by the mucocilary system. , PTM:C-, O-and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis. , PTM:Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide. , similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain. , similarity:Contains 2 VWFC domains. , similarity:Contains 4 VWFD domains. , subunit:Multimeric. Interacts with H. pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) . , tissue specificity:Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. ,
Gene Name: MUC5AC MUC5
Protein Name: Mucin 5AC
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基因ID
- 4586
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UniProt
- P98088
抗原
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