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MICA 抗体 (AA 30-110)

This 兔 多克隆 antibody specifically detects MICA in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8122916
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MICA 抗体 (AA 30-110) (ABIN8122916)

抗原

See all MICA 抗体
MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

适用

  • 117
  • 18
  • 14
  • 12
  • 11
  • 8
  • 7
  • 4
  • 4
  • 1
人, 小鼠, 大鼠

宿主

  • 57
  • 45
  • 17
兔

克隆类型

  • 66
  • 50
  • 2
多克隆

标记

  • 67
  • 13
  • 9
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MICA antibody is un-conjugated

应用范围

  • 66
  • 41
  • 39
  • 26
  • 19
  • 14
  • 11
  • 9
  • 8
  • 6
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-110

    原理

    MICA Antibody

    特异性

    MICA Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 30-110

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

    别名

    MICA

    背景

    Background: This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014],

    Gene Name: MICA PERB11.1

    Protein Name: MHC class I polypeptide-related sequence A (MIC-A)

    基因ID

    100507436

    UniProt

    Q29983

    途径

    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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