LRP6 抗体
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北京 101111
Quick Overview for LRP6 抗体 (ABIN8122682)
抗原
See all LRP6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- LRP6 Rabbit mAb
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特异性
- This antibody detects endogenous levels of LRP6 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1198-1370) antibody
LRP6 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A3F5 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1546-1560) antibodyVerified LRP6 适用: 人 IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1531-1560), (C-Term) antibodyLRP6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01837 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (C-Term) antibodyLRP6 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal AFfirm8319 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (pSer1490) antibodyLRP6 适用: 人 WB, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 981-1213) antibodyLRP6 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-150) antibodyLRP6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (pSer1420) antibodyLRP6 适用: 人, 小鼠 ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 981-1213) antibodyLRP6 适用: 人 IHC 宿主: 小鼠 Monoclonal C3 unconjugated
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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别名
- LRP6
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背景
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Synonyms: Low-density lipoprotein receptor-related protein 6 (LRP-6)
Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP-(regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined. [provided by RefSeq, Dec 2009],
Gene Name: LRP6
Protein Name: LRP6
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基因ID
- 4040
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UniProt
- O75581
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途径
- WNT signaling, Tube Formation
抗原
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