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LIM Domain Kinase 1 抗体 (pSer310)

The 兔 多克隆 anti-LIM Domain Kinase 1 antibody (ABIN8122645) specifically detects LIM Domain Kinase 1 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8122645
发货至: 中国
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Quick Overview for LIM Domain Kinase 1 抗体 (pSer310) (ABIN8122645)

抗原

See all LIM Domain Kinase 1 (LIMK1) 抗体
LIM Domain Kinase 1 (LIMK1)

适用

  • 134
  • 60
  • 53
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 114
  • 21
  • 3
兔

克隆类型

  • 116
  • 22
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This LIM Domain Kinase 1 antibody is un-conjugated

应用范围

  • 102
  • 43
  • 32
  • 26
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  • 17
  • 15
  • 8
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  • 6
  • 6
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 24
    • 17
    • 15
    • 15
    • 8
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer310

    原理

    LIMK1 (Phospho Ser310) Antibody

    特异性

    This antibody detects endogenous levels of LIMK1 (Phospho-Ser310) at Human, Mouse,Rat

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized peptide derived from human LIMK1 (Phospho-Ser310)

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    LIM Domain Kinase 1 (LIMK1)

    别名

    LIMK1

    背景

    Synonyms: LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)

    Background: There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cog

    Gene Name: LIMK1 LIMK

    Protein Name: LIMK1 (Phospho-Ser310)

    基因ID

    3984

    UniProt

    P53667

    途径

    Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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