IFNB1 抗体 (AA 91-140)
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北京 101111
Quick Overview for IFNB1 抗体 (AA 91-140) (ABIN8122308)
抗原
See all IFNB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 91-140
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原理
- IFN-β Antibody
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特异性
- The antibody detects endogenous IFN-β
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic peptide from human protein at AA range: 91-140
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亚型
- IgG
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应用备注
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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别名
- IFN-beta
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背景
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Synonyms: Interferon beta (IFN-beta, Fibroblast interferon)
Background: This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens.The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015],
Gene Name: IFNB1 IFB IFNB
Protein Name: Interferon beta (IFN-beta) (Fibroblast interferon)
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基因ID
- 3456
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UniProt
- P01574
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途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
抗原
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